Shoot the drop targets and rollover lanes for bonus advance. Avoid the veri-target (Death) until Ball 5 (double bonus ball)
Vari-Target on the left is a drain monster.
Get the 3 top lanes to lit more bonus and X2 bonus
Build bonus as much as you can
If you can hit the veri-target solidly, it will award 5K points and 5 bonus advances. The return on this is often really harsh though.
The drop targets also advance bonus and generally feed the ball in a nice direction, especially if you hit the top drops.
Plunge the "I" if you can - you can't get it any other way. Any top lane helps, though!